Gianni Pedrizzetti Publications

Main Publications

This is a private page; it contains material that may be subjected to copyright that cannot be downloaded without an explicit authorization. Any unauthorized download can represent an infringement of the applicable laws and is performed under own responsibility.

The material contained herein is meant to provide a resource available after invitation only. Who landed on this page without an invitation should leave this page immediately and is not authorized to download any content.

Forthcoming Articles

2024

Faganello G, Collia D, Pagura L, Croatto E, Tosoni L, Toritto P, Hizumo H, Pedrizzetti G, Di Lenarda A. Impact of left ventricular hemodynamic forces in adult patients with treated aortic coarctation and preserved left ventricular systolic function. Echocardiography 2024. http://dx.doi.org/10.1111/echo.15742

2023

[Cover image]: J Am Soc Echocardiogr 2023; 36(8).

Pedrizzetti G. Atrial Strain in Cardiovascular Magnetic Resonance Imaging, a Sensitive Companion of Ventricular Strain. Int J Cardiol 2023. https://doi.org/10.1016/j.ijcard.2023.131604

Pellegrino A, Toncelli L, Pasquini L, Masini G, Mecacci F, Pedrizzetti G, Modesti PA. Left ventricular remodeling in twin pregnancy non-invasively assessed using hemodynamic forces and pressure-volume relation analysis: observational, prospective, cohort study. American Journal of Physiology-Heart and Circulatory Physiology 2023. https://doi.org/10.1152/ajpheart.00699.2023

Laenens D, van der Bijl P; Galloo X, Rossi AC, Tonti G, Reiber JH, Pedrizzetti G, Marsan NA; Bax JJ. Evolution of echocardiography-derived hemodynamic force parameters after cardiac resynchronization therapy. Am J Cardiol 2023; 209:138-145. https://doi.org/10.1016/j.amjcard.2023.09.098
- Related Editorial

Collia D, Angeli E, Careddu L, Pedrizzetti G. Analysis of the distribution and orientation of oxygenated and non-oxygenated blood in a Double Outlet Right Ventricle. Phys Fl 2023;35(9):0163885. https://doi.org/10.1063/5.0163885
- Related Editorial

Fabiani I, Pugliese NR, Pedrizzetti G, Tonti G, Chubuchny V, Taddei C, Gimelli A, Del Punta L, Balletti A, Masi S, Casitglione V, Cameli M, Emdin M, Giannoni A. Hemodynamic Forces as Predictors of Cardiac Remodeling and Outcome in Heart Failure with Reduced Ejection Fraction Treated with Sacubitril/Valsartan. ESC Heart Failure 2023;10:2927:2938. http://doi.org/10.1002/ehf2.14346

Mele D, Beccari R, Pedrizzetti G. Effect of aging on intraventricular kinetic energy and energy dissipation. Journal of Cardiovascular Development and Disease 2023,10:308. https://doi.org/10.3390/jcdd10070308

Vos JL, Raafs AG, Henkens MTHM, Pedrizzetti G, van Deursen CJ, Rodwell L, Heymans SRB, Nijveldt R. CMR-derived left ventricular intraventricular pressure gradients identify different patterns associated with prognosis in dilated cardiomyopathy. Eur Hear J, Cardiovasc Imag 2023. https://doi.org/10.1093/ehjci/jead083

Sato T, Matsubara D, Agger P, Wang Y, Pedrizzetti G, Banerjee A. Contraction Patterns of Post-Fontan Single Right Ventricle versus Normal Left and Right Ventricles in Children: Insights from Principal Strain Analysis. J Am Soc Echocardiogr 2023;36:803-894. https://doi.org/10.1016/j.echo.2023.03.004

Vairo A, Zaccaro L, Ballatore A, Airale L, D'Ascenzo F, Alunni G, Conrotto F, Scudeler L, Mascaretti D, Miccoli D, La Torre M, Rinaldi M, Pedrizzetti G, Salizzoni S, De Ferrari GM. Acute modification of Hemodynamic Forces in patients with severe aortic stenosis after Transcatheter Aortic Valve Implantation. J Clin Med 2023. https://doi.org/10.3390/jcm12031218

Collia D, Pedrizzetti G, Sato T, Matsubara D, Zovatto L, Gei M, Banerjee A, Pedrizzetti G. Interplay between Geometry, Fluid Dynamics Function and Structure in the Ventricles of the Human Heart. Phys Rev Applied 2023; 19:014006. http://dx.doi.org/10.1103/PhysRevApplied.19.014006

2022

Faganello G, Pagura L, Collia D, Barbati G, Paldino A, Dal Ferro M, Croatto E, Sinagra G, Pedrizzetti G, Di Lenarda A. Prognostic value of echocardiographic evaluation of cardiac mechanics in patients with aortic stenosis and preserved left ventricular ejection fraction. Int J Cardiovasc Imag 2022. https://doi.org/10.1007/s10554-022-02756-z

Related Editorial

Laenens D, van der Bijl P, Rossi AC, Pedrizzetti G, Reiber JHC, Ajmone Marsan N, Bax JJ. Introduction to Hemodynamic Forces by Echocardiography. Int J Cardiovasc Imag 2022. https://doi.org/10.1016/j.ijcard.2022.11.019

Kheradvar A, Pedrizzetti G. State of Energy of Ventricular Flow: a cause or the first indicator of adverse remodeling? Int J Cardiol 2022. https://doi.org/10.1016/j.ijcard.2022.09.042

Collia D, Pedrizzetti G. The influence of mitral valve asymmetry for an improved choice of valve repair or replacement. Fluids 2022; 7:293. https://doi.org/10.3390/fluids7090293

Li L, Jani V, Craft M, Olson J, Schuster A, Pedrizzetti G, Danford D, Kutty S. Ventricular Flow Profile in Young Patients with Single Left Ventricle Fontan using Echocardiographic Contrast Particle Imaging Velocimetry. J Am Soc Echocardiogr 2022. https://doi.org/10.1016/j.echo.2022.08.011

La Gerche A, Pedrizzetti G, Ranieri B, D'Andrea A, Bossone E. On the characterization of athlete s heart using 3D echocardiography. Eur J Prev Cardiol 2022; 29:1592. https://doi.org/10.1093/eurjpc/zwac117

Loke Y-H, Capuano F, Kollar S, Cibis M, Kitslaar P, Balaras E, Reiber JHC, Pedrizzetti G, Olivieri L. Abnormal Diastolic Hemodynamic Forces: A Link Between Right Ventricular Wall Motion, Intracardiac Flow and Pulmonary Regurgitation in Repaired Tetralogy of Fallot. Front Cardiovasc Med 2022;9:929470. doi: 10.3389/fcvm.2022.929470

Bisegna, P, Parenti-Castelli V, Pedrizzetti G. Biomechanics in AIMETA. In: Rega, G. (eds) 50+ Years of AIMETA. Springer, Cham 2022. https://doi.org/10.1007/978-3-030-94195-6_28

Collia D, Libero G, Pedrizzetti G, Ciriello V. Surrogate models provide new insights on metrics based on blood flow for the assessment of left ventricular function. Sc Rep 2022; 12:8695. doi: 10.1038/s41598-022-12560-3

Monosilio S, Filomena D, Luongo F, Sannino M, Cimino S, Neccia M, Mariani MV, Birtolo IL, Benedetti G, Tonti G, Pedrizzetti G, Vizza CD, Maestrini V, Agati L. Cardiac and vascular remodeling after 6 months of therapy with Sacubitril/Valsartan: mechanistic insights from advanced echocardiographic analysis. Front Cardiovasc Med 2022; 9:883769. doi: 10.3389/fcvm.2022.883769

Fiorencis A, Pepe M, Smarrazzo V, Martini M, Severino S, Pergola V, Evangelista M, Incarnato P, Previtero M, Maglione M, Iliceto S, Pedrizzetti G, Mele D. Noninvasive Evaluation of Intraventricular Flow Dynamics by the HyperDoppler Technique: First Application to Normal Subjects, Athletes, and Patients with Heart Failure. J Clin Med 2022;11:2216. https://doi.org/10.3390/jcm11082216

Toncelli L, Pasquini L, Masini G, Orlandi M, Paci G, Mecacci F; Pedrizzetti G, Galanti G. Difference in cardiac remodeling between female athletes and pregnant women: a case control study. Cardiovasc Ultrasound 2022;20:10.

Vos JL, Leiner T, van Dijk APJ, Pedrizzetti G, Alenezi F, Rodwell L, van derWegen CTPM, Post MC, Driessen MMP, Nijveldt R. Left ventricle CMR derived intraventricular pressure gradients among patients with precapillary pulmonary hypertension. Eur Heart J, Cardiovasc Imag 2022. https://doi.org/10.1093/ehjci/jeab294

Filomena D, Cimino S, Monosilio S, Galea N, Mancuso G, Francone M, Tonti G, Pedrizzetti G, Maestrini V, Fedele F, Agati L. Impact of intraventricular hemodynamic forces misalignment on left ventricular remodeling after myocardial infarction. ESC Heart Failure 2022;9:496-505. http://doi.org/10.1002/ehf2.13719

Orlandi M, Bini V, Leone B, Zappelli E, Pedrizzetti G, Stefani L. Home-based exercise program maintains normal Right Ventricle function in Renal Transplant Recipients. J Sports Med Phys Fitness 2022; 62:412-417. DOI: 10.23736/S0022-4707.21.12537-X.

[Monographic Textbook]: Pedrizzetti G. Fluid Mechanics for Cardiovascular Engineering. Springer, Cham 2022 (ISBN 978-3-030-85942-8). DOI: 10.1007/978-3-030-85943-5.

2021

Vallelonga F, Airale L, Tonti G, Argulian E, Milan A, Narula J, Pedrizzetti G. An Introduction to Hemodynamic Force Analysis: Analysis: moving into the new frontier of cardiac deformation analysis. J Am Heart Assoc 2021;10:e023417. https://doi.org/10.1161/JAHA.121.023417

Ferrara F, Capuano F, Cocchia R, Ranieri B, Contaldi C, Lacava G, Capone V, Chianese S, Rega S, Annunziata R, Sepe C, Salzano A, Citro R, D'Andrea A, Mauro C, Cademartiri F, Pedrizzetti G, Bossone E. Reference Ranges of Left Ventricular Hemodynamic Forces in Healthy Adults: A Speckle-Tracking Echocardiographic Study. J Clin Med 2021;10:5937. https://doi.org/10.3390/jcm10245937

de la Pena-Almaguer E, Hautemann D, Pedrizzetti G. Computed tomography derived left ventricular inward displacement as a novel tool for quantification of segmental wall motion abnormalities. Int J Cardiovasc Imag 2021. DOI:10.1007/s10554-021-02435-5.

Airale L, Vallelonga F, Forni T, Leone D, Magnino C, Avenatti E, Iannaccone A, Astarita A, Mingrone G, Cesareo M, Giordana C, Omed P, Moretti C, Veglio F, Pedrizzetti G, Milan A. A novel approach to left ventricular filling pressure assessment: the role of hemodynamic forces analysis. Front Cardiovasc Med 2021; DOI: 10.3389/fcvm.2021.704909.

Collia D, Zovatto L, Tonti G, Pedrizzetti G. Comparative Analysis of Blood Flow in the Right Ventricle of the Human Heart. Frontiers in Bioengineering and Biotechnology-Biomechanics 2021; 9:667408. DOI:10.3389/fbioe.2021.667408

Pedrizzetti G, Faganello G, Croatto E, Di Lenarda A. Heart s Hemodynamic Power Differentiates Normal from Diseased Right Ventricles. J Biomech 2021; 119:110312. DOI:10.1016/j.jbiomech.2021.110312

Kheradvar A, Vannan M, Dasi LP, Pedrizzetti G. The Effect of Aortic Root Anatomy and Vortex Flow Induced Shear Stress on the Aortic Valve Leaflets. Eur Heart J, Cardiovasc Imag 2021. DOI:10.1093/ehjci/jeab031

Ferraro D, D Alesio G, Camboni D, Zinno C, Costi L, Haberbusch M, Aigner P, Maw M, Schl glhofer T, Unger E, Aliperta A, Bernini F, Casieri V, Terlizzi D, Giudetti G, Carpaneto J, Pedrizzetti G, Micera S, Lionetti V, Moscato F, Massari L, Oddo CM. Implantable Fiber Bragg Grating sensor for continuous heart activity monitoring: ex-vivo and in-vivo validation. IEEE Sensors Journal 2021. DOI:10.1109/JSEN.2021.3056530

Bianchi V, Martiniello AR, Mangual J, Tavoletta V, Pedrizzetti G, Tonti G, Caso VM, Caso P, D Onofrio A. Impact of synchronous atrioventricular delay optimization on left ventricle flow force angle evaluated by echocardiographic particle image velocimetry . Journal of Interventional Cardiac Electrophysiology 2021. DOI:10.1007/s10840-020-00923-7

2020

Thomas L, Muraru D, Popescu B, Sitges M, Rosca M, Pedrizzetti G, Heinen M, Donal E, Badano LP. Evaluation of left atrial size and function: relevance for clinical practice. J Am Soc Echocardiogr 2020; 33:934-952. DOI:10.1016/j.echo.2020.03.021

Faganello G, Collia D, Furlotti S, Pagura L, Zaccari M, Pedrizzetti G, Di Lenarda A. Reference values for the normal left ventricle: an integrated approach to cardiac mechanics. Int J Cardiovasc Imag 2020; 36:2173-2185. DOI:10.1007/s10554-020-01934-1

Vriz O, Arshia F, Ahmeda M, Alhumaida M, Galzerano D, Aladmawia M, Alshahida M, Pedrizzetti G. Cavitation phenomenon in mechanical prosthetic valves: not only microbubbles. Echocardiography 2020: 37:876-882. DOI: 10.1111/echo.14692

Sato T, Calderon RJC, Klas B, Pedrizzetti G, Banerjee A. Simultaneous Volumetric and Functional Assessment of the Single Right Ventricle After Fontan Palliation, Utilizing Three-dimensional Speckle Tracking Echocardiography. Circ J doi: 10.1253/circj.CJ-19-0926.

Year 2020 Circulation Journal Award (clinical investigation section)

2019

Tanacli R, Hashemi D, Lapinskas T, Edelmann F, Gebker R, Pedrizzetti G, Schuster A, Nagel E, Pieske B, D ngen HD, Kelle S. Range Variability in CMR Feature Tracking Multilayer Strain across Different Stages of Heart Failure. Sci Rep 2019: 9:16478. DOI:10.1038/s41598-019-52683-8

Pedrizzetti G, Tanacli R, Lapinskas T, Zovatto L, Pieske B, Tonti G, Kelle S. Integration between volumetric change and strain for describing the global mechanical function of the left ventricle. Med Eng Phys 2019; 74:65-72. DOI:10.1016/j.medengphy.2019.07.016

Pedrizzetti G. On the computation of hemodynamic forces in the heart chambers. J Biomech 2019; 95:109323. DOI:10.1016/j.jbiomech.2019.109323

Collia D, Vukicevic M, Meschini V, Zovatto L, Pedrizzetti G. Simplified mitral valve modelling for prospective clinical application of left ventricular fluid dynamics. J Comput Phys 2019; 398:108895. DOI:10.1016/j.jcp.2019.108895

Mele D, Smarrazzo V, Pedrizzetti G, M. Bertini, Ferrari R. Vortex analysis in cardiac resynchronization therapy: A new challenge? Echocardiography. DOI: 10.1111/echo.14477

Kheradvar A, Rickers C, Morisawa D, Kim M, Hong GR, Pedrizzetti G. Diagnostic and Prognostic Significance of Cardiovascular Vortex Formation. J Cardiol 2019; 74:403-411. DOI:10.1016/j.jjcc.2019.05.005

Miskinyte E, Bucius P, Erley J, Zamani M, Tanacli R, Stehning C, Schneeweis C, Lapinskas T, Pieske B, Falk V, Gebker R, Pedrizzetti G, Solowjowa N, Kelle S. Assessment of Global Longitudinal and Circumferential Strain Using Computed Tomography Feature Tracking: intra-individual comparison with CMR Feature Tracking and myocardial Tagging. J Clin Med 2019; 8:1423. DOI:10.3390/jcm8091423.

Collia D, Zovatto L, Pedrizzetti G. Analysis of Mitral Valve Regurgitation by Computational Fluid Dynamics. APL Bioeng 2019;3:036105. DOI: 10.1063/1.5097245.

Pedrizzetti G, Lapinskas T, Tonti G, Stoiber L, Zaliunas R, Pieske B, Kelle S. The relationship between ejection fraction and strain permits a more accurate assessment of left ventricular systolic function. JACC Cardiovasc Imaging 2019; 12:1893-1895. DOI:10.1016/j.jcmg.2019.03.019

Filomena D, Cimino S, Maestrini V, Cantisani D, Petronilli V, Mancone M, Tonti G, Pedrizzetti G, Agati L. Changes in Intraventricular Flow Patterns after MitraClip Implant in Patients with Functional Severe Mitral Regurgitation. J Am Soc Echocardiogr 2019; 32:1250 1253.e1. DOI:10.1016/j.echo.2019.05.022

Dal Ferro M, De Paris V, Collia D, Stolfo D, Caiffa T, Barbati G, Korcova R, Pinamonti B, Zovatto L, Zecchin M, Sinagra G, Pedrizzetti G. Left ventricular response to cardiac resynchronization therapy: insights from hemodynamic forces computed by speckle tracking. Front Cardiovasc Med 2019; 6: 59. DOI:10.3389/fcvm.2019.00059

Martiniello AR, Bianchi V, Tonti G, Cioppa C, Tavoletta V, D'Onofrio A, Caso VM, Pedrizzetti G, Caso P. Combined flow-based imaging assessment of optimal cardiac resynchronization therapy pacing vector: a case report J Med Case Rep 2019; 13: 161. DOI:10.1186/s13256-019-2048-1

Bianco F, Cicchitti V, Bucciarelli V, Chandra A, Di Girolamo E, Pedrizzetti G, Tonti G, De Caterina R, Gallina S. Intraventricular flow patterns during right ventricular apical pacing. Open Heart 2019; 6: e001057. doi:10.1136/openhrt-2019-001057.

Fukui M, Xu J, Abdelkarim I, Sharbaugh MS, Thoma FW, Althouse A, Pedrizzetti G, Cavalcante J. Global Longitudinal Strain Assessment by Computed Tomography in Severe Aortic Stenosis Patients - Feasibility Using Feature Tracking Analysis. Journal of Cardiovascular Computed Tomography;2019; 13:157-162. DOI: 10.1016/j.jcct.2018.10.020.

Mele D, Smarrazzo V, Pedrizzetti G, Capasso F, Pepe M, Severino S, Luisi GA, Maglione M, Ferrari R. Intracardiac Flow Analysis: Techniques and Potential Clinical Applications. J Am Soc Echocardiogr 2018; 32: 319-332. DOI:10.1016/j.echo.2018.10.018

Lapinskas T, Pedrizzetti G, Stoiber L, D ngen HD,Edelmann F, Pieske B, Kelle S. The intraventricular hemodynamic forces estimated using routine CMR cine images: A new marker of failing heart. JACC Imaging 2019; 12:377-379. DOI: 10.1016/j.jcmg.2018.08.012.

Celotto C, Zovatto L, Collia D, Pedrizzetti G. Influence of mitral valve elasticity on flow development in the left ventricle. Eur J Mech B/Fuids 2019; 75:110-118. DOI:10.1016/j.euromechflu.2018.11.018

2018

Arvidsson PM, T ger J, Pedrizzetti G, Heiberg E, Borgquist R, Carlsson M, Arheden H. Hemodynamic forces using four-dimensional flow MRI: an independent biomarker of cardiac function in heart failure with left ventricular dyssynchrony?. AJP-Heart and Circ 2018; 315:H1627-H1639. DOI:10.1152/ajpheart.00112.2018.

Related Editorial

Zovatto L, Pedrizzetti G. Optimal entry flow in helical vessel. Fluid Dynamics Research2018; 50:065503. DOI:10.1088/1873-7005/aadefd.

Kim I-C, Hong G-R, Pedrizzetti G, Shim CY, Kang S-M, Chung N Usefulness of Left Ventricular Vortex Flow Analysis for Predicting Clinical Outcomes in Patients with Chronic Heart Failure: A Quantitative Vorticity Imaging Study Using Contrast Echocardiography. Ultrasound Med Biol 2018; 44:1951-1959. DOI:10.1016/j.ultrasmedbio.2018.05.015

Minetti E, Klika R, Ingletto C, Mascherini G, Pedrizzetti G, Stefani L. Changes in global longitudinal strain in renal transplant recipients following 12 months of exercise. Internal and Emergency Medicine 2018. DOI: 10.1007/s11739-018-1893-z

T ger J, Arvidsson PM, Block J, Kanski M, Pedrizzetti G, Carlsson M, Arheden H, Heiberg E. Hemodynamic forces in the left and right ventricles of the human heart using 4D flow magnetic resonance imaging: phantom validation, reproducibility, sensitivity to respiratory gating and free analysis software. PLOS One 2018; 13:e0195597. DOI: 10.1371/journal.pone.0195597

Dal Ferro M, Stolfo D, De Paris V, Lesizza P, Korcova R, Collia D, Tonti G, Sinagra G, Pedrizzetti G. Cardiac Fluid Dynamics meets Deformation Imaging. Cardiovascular Ultrasound 2018; 16:4. DOI: 10.1186/s12947-018-0122-2

2017

Galanti G., Pedrizzetti G., Pedri S., Stefani L. 2D longitudinal LV speckle tracking strain pattern in breast cancer survivors: sports activity vs exercise as prescription model. Internal and Emergency Medicine 2017; 12:1149-1157.

Pedrizzetti G, Arvidsson PM, T ger J, Borgquist R, Domenichini F, Arheden H, Heiberg E. On estimating intraventricular hemodynamic forces from endocardial dynamics: a comparative study with 4D flow MRI. J Biomech 2017; 60:203-210. DOI:10.1016/j.jbiomech.2017.06.046

Omar AMS, Narula S, Abdel-Rahman MA, Pedrizzetti G, Raslan H, Rifaie O, Narula J, Sengupta PP. Precision Phenotyping in Heart Failure and Pattern Clustering of Ultrasound Data for the Assessment of Diastolic Dysfunction. JACC Imaging 2017. doi:10.1016/j.jcmg.2016.10.012

Siciliano M, Migliore F, Badano L, Bertaglia E, Pedrizzetti G, Cavedon S, Zorzi A, Corrado D, Iliceto S, Muraru D. Cardiac Resynchronization Therapy by Multipoint Pacing Improves the Acute Response of Left Ventricular Mechanics and Fluid Dynamics: a Three-Dimensional and Particle Image Velocimetry Echo Study. Europace 2017; 19:1833-1840. doi:10.1093/europace/euw331

Bisegna P, Parenti-Castelli V, Pedrizzetti G. Special issue on Advances in biomechanics: from foundations to applications. Meccanica 2017. DOI: 10.1007/s11012-016-0572-2.

2016

Domenichini F, Pedrizzetti G. Hemodynamic Forces in a Model Left Ventricle. Phys Rev Fluids 2016 1 083201. doi:10.1103/PhysRevFluids.1.083201.

Stefani S, Pedrizzetti G, Pedri S, Minetti E, Mandoli M, Tosi B, Galanti G. Cardiovascular Outcomes in Renal Transplant Recipients: Feasibility and Clinical Role of 2D Speckle Tracking to Assess Myocardial Function. J Funct Morphol Kinesiol 2016 1 109. https://doi.org/10.3390/jfmk1010109

Stefani S, Pedrizzetti G, Galanti G. Clinical Application of 2D Speckle Tracking Strain for Assessing Cardio-Toxicity in Oncology. J Funct Morphol Kinesiol 2016 1 343. https://doi.org/10.3390/jfmk1040343

Arvidsson PM, T ger J, Carlsson M, Steding-Ehrenborg K, Pedrizzetti G, Heiberg E, Arheden H. Left and right ventricular hemodynamic forces in healthy volunteers and elite athletes assessed with 4D flow magnetic resonance imaging. AJP-Heart and Circ 2016 . doi:10.1152/ajpheart.00583.2016.

Pedrizzetti G, Claus P, Kilner PJ, Nagel E. Principles of cardiovascular magnetic resonance feature tracking and echocardiographic speckle tracking for informed clinical use. J Cardiovasc Magn Reson 2016; 18:51. doi:10.1186/s12968-016-0269-7.

Martiniello AR, Pedrizzetti G, Bianchi V, Tonti G, D'Onofrio A, Caso P. Left ventricular pacing vector selection by novel Echo-PIV analysis for optimization of quadripolar cardiac resynchronization device: a case report. Journal of Medical Case Reports 2016; 10:191.

Pedrizzetti G, Martiniello AR, Bianchi V, D'Onofrio A, Caso P, Tonti G. Changes in electrical activation modify the direction of left ventricular flow momentum: novel observations using Echocardiographic Particle Image Velocimetry. Eur Heart J, Cardiovasc Imag 2016; 17:203-209.

Son JW, Hong GR , Hong W, Kim M, Houle H, Vannan MA, Pedrizzetti G, Chung N. Differences in aortic vortex flow pattern between normal and patients with stroke: qualitative and quantitative assessment using transesophageal contrast echocardiography. Int J Cardiovasc Imaging 2016. DOI: 10.1007/s10554-015-0818-4.

Zovatto L, Pedrizzetti G. Fluid flow in a helical vessel in presence of a stenosis. Meccanica 2016. DOI: 10.1007/s11012-015-0297-7.

2015

Claus P, Omar AMS, Pedrizzetti G, Sengupta PP, Nagel E. Tissue Tracking Technology for Assessing Cardiac Mechanics. JACC Imaging 2015; 12:1444-60.

Pedrizzetti G, Vlachos PP, Little WC, Sotiropoulos F, Gharib M, Kheradvar A. Comments on Defining the Contribution of Diastolic Vortex Ring to Left Ventricular Filling. J Am Coll Cardiol 2015; 65:2573-2574.

Pedrizzetti G, Martiniello AR, Bianchi V, D'Onofrio A, Caso P, Tonti G. Cardiac Fluid Dynamics Anticipates Heart Adaptation. J Biomech 2015; 48:388-391.

Domenichini F, Pedrizzetti G. Asymptotic Model of Fluid-Tissue Interaction for Mitral Valve Dynamics. CVET 2015; 6:95-104.

Pedrizzetti G, Sengupta PP. Vortex Imaging: New Information Gain From Tracking Cardiac Energy Loss. Eur Heart J, Cardiovasc Imag 2015; 16:719-720.

Pedrizzetti G, Sengupta PP. Newer Methods to Assess Diastolic Function. Chapter 43, in "ASE s Comprehensive Echocardiography, 2e" (Editors: Lang RM, Goldstein SA, Kronzon I, Khandheria BK, Mor-Avi V). Elsevier 2015.

Pedrizzetti G, Domenichini F. Left Ventricular Fluid Mechanics: the long way from theoretical models to clinical applications. Ann Biomed Eng 2015; 43:26-40.

Voigt JU, Pedrizzetti G, Lysyansky P, Marwick TH, Houle H, Baumann R, Pedri S, Ito Y, Abe Y, Metz S, Song J, Hamilton J, Sengupta P, Kolias TJ, d Hooge J, Aurigemma GP, Thomas JD, Badano L. Definitions for a common standard for 2D speckle tracking echocardiography: consensus document of the EACVI/ASE/Industry Task Force to standardize deformation imaging. Eur Heart J, Cardiovasc Imag 2015; 16:1-11. & J Am Soc Echocardiogr 2015; 28:183-93.

Busato A, Balconi G, Vismara V, Bertel L, Tonti G, Pedrizzetti G. Strain analysis of masseter muscle by ultrasound. J Biol Regul Homeost Agents 2015;29(3 Suppl 1):74-81.

2014

Pedrizzetti G, Sengupta S, Caracciolo G, Park CS, Amaki M, Goliasch G, Narula J, Sengupta PP. Three-dimensional Principal Strain Analysis for Characterizing Subclinical Changes in Left Ventricular Function. J Am Soc Echocardiogr 2014; 27;1041-50.

Related Editorial

Kutty S, Li L, Danford DA, Houle H, Xiao Y, Pedrizzetti G, Porter TR. Effects of Right Ventricular Hemodynamic Burden on Intraventricular Flow in Tetralogy of Fallot: An Echo Contrast Particle Imaging Velocimetry Study. J Am Soc Echocardiogr 2014; 27:1311-8.

Falahatpisheh A, Pedrizzetti G, Kheradvar A. Three-Dimensional Reconstruction of Cardiac Flows Based on Multi-Planar Velocity Fields. Experiments in Fluids 2014; 55:1848.

Stefani L, De Luca A, Toncelli L, Pedrizzetti G, Galanti G. 3D Strain Helps Relating LV Function to LV and Structure in Athletes. Cardiovasc Ultrasound 2014; 2:33.

Pedrizzetti G, La Canna G, Alfieri O, Tonti G. The vortex - an early predictor of cardiovascular outcome. Nature Reviews Cardiology 2014; 11:545 53.

Amaki M, Savino J, Ain DL, Sanz J, Pedrizzetti G, Kulkarni H, Narula J, Sengupta PP. Diagnostic Concordance of Echocardiography and CMR-based Feature Tracking for Differentiating Constrictive Pericarditis from Restrictive Cardiomyopathy. Circ Cardiovasc Imaging 2014;7:819-827.

Agati L, Cimino S, Tonti G, Cicogna F, Petronilli V, Pedrizzetti G. Quantitative Analysis of Intraventricular Blood Flow Dynamics by Echocardiographic Particle Image Velocimetry in Patients with Acute Myocardial Infarction at Different Stages of Left Ventricular Dysfunction. Eur Heart J Cardiovasc Imaging 2014; 15:1203-1212.

Pedrizzetti G, Mangual J, Tonti G. On the Relationship between Global Longitudinal Strain and Ejection Fraction. J Biomech 2014; 47:746-749.

2013

[Cover image]: Nature Reviews Cardiology 2013; 10 (12 issues).

[Cover image]: J Am Coll Cardiol Img 2013; 6(5).

Hong GR, KIm M, Pedrizzetti G, Vannan MA. Current Clinical Application of Intracardiac Flow Analysis Using Echocardiography. J Cardiovascular Ultrasound 2013;21:155 162.

Mangual JO, De Luca A, Kraigher-Krainer E, Toncelli L, Shah A, Solomon S, Galanti G, Domenichini F, Pedrizzetti G. Comparative numerical study on left ventricular fluid dynamics after dilated cardiomyopathy. J Biomech 2013;46:1611 1617.

Caracciolo G, Goliasch G, Amaki M, Bansal M, Nakabo A, Haruiko A,Scott L, Lipar L, Pedrizzetti G, Narula J, Sengupta PP. Myocardial stretch in early systole is a key determinant of the synchrony of left ventricular mechanical activity in vivo. Circulation Journal 2013; 77:2526-2534.

Goliasch G, Goscinska-Bis K, Caracciolo G, Nakabo A, Smolka G, Pedrizzetti G, Narula J, Sengupta PP. CRT Improves Left Ventricular Filling Dynamics: Insights From Echocardiographic Particle Imaging Velocimetry. J Am Coll Cardiol Img 2013; 6:704-713.

Mangual JO, F ll D, Jung B, Pedrizzetti G, Kheradvar A. Aging does not Affect Radial Viscoelastic Behavior of the Left Ventricle. Cardiology 2013; 125:38-49.

Abe H, Caracciolo G, Kheradvar A, Pedrizzetti G, Khandheria BK, Narula J, Sengupta PP. Contrast echocardiography for assessing left ventricular vortex strength in heart failure: a prospective cohort study. Eur Heart J, Cardiov Imag 2013; 14:1049-1060.

Dini FL, Guarini G, Pedrizzetti G, Miccoli M, Zito MC, Baggiani A, Conti U, Di Bello V, Marzilli M. Ultrasound Assessment of the Force-frequency Relationship from the Law of Conservation of Momentum in Patients with Left Ventricular Dysfunction. Ultrasound in Medicine & Biology 2013; 39:585-591.

2012

[Monographic Book]: Kheradvar A, Pedrizzetti G. Vortex Formation in the Cardiovascular System. Springer-Verlag, London UK 2012 (ISBN 978-1-4471-2287-6).

[Cover image]: J Am Coll Cardiol Img 2012; 5(3).

[Cover image]: Ann Biomed Eng 2012; 40(8).

Mangual JO, De Luca A, Toncelli L, Domenichini F, Galanti G, Pedrizzetti G. Three Dimensional Reconstruction of the Functional Strain-Line Pattern in the Left Ventricle from 3D Echocardiography. Circ Cardiovasc Imaging 2012; 5:808-809.

Padiyath A, Gribben P, Li L, Rangamani S, Schuster A, Danford DA, Pedrizzetti G, Kutty S. Echocardiography and cardiac magnetic resonance based feature tracking in the assessment of myocardial mechanics in tetralogy of fallot: an intermodality comparison. Echocardiography 2012; 30:203-210.

Bhatti S, Al-Khalidi H, Hor K, Hakeem A, Taylor M, Quyyumi AA, Oshinski J, Pecora AL, Kereiakes D, Chung E, Pedrizzetti G, Miszalski-Jamka T, Mazur W. Assessment of Myocardial Contractile Function Using Global and Segmental Circumferential Strain following Intracoronary Stem Cell Infusion after Myocardial Infarction: MRI Feature Tracking Feasibility Study. ISRN Radiology 2012; 2013:371028 (http://dx.doi.org/10.5402/2013/371028).

Stefani L, Pedrizzetti G, De Luca A, Mercuri R, Innocenti G, Toncelli L, Vono MCR, Pedri S, Galanti G. Assessment of left ventricle twisting in athletes with Bicuspid Aortic Valve. British Journal of Medicine and Medical Research 2012; 2:575-586.

Pedrizzetti G, Kraigher-Krainer E, De Luca A, Caracciolo G, Mangual JO, Shah A, Toncelli L, Domenichini F, Tonti G, Galanti G, Sengupta PP, Narula J, Solomon S. Functional Strain-line Pattern in the Human Left Ventricle. Phys Rev Lett 2012; 109:048103.

Sengupta PP, Pedrizzetti G, Narula J. Multiplanar Visualization of Blood Flow Using Echocardiographic Particle Imaging Velocimetry. J Am Coll Cardiol Img 2012; 5:566-569.

Sengupta PP, Pedrizzetti G, Kilner P., Kheradvar A, Ebbers T, Frazer A, Tonti G, Narula J. Emerging Trends in CV Flow Visualization. J Am Coll Cardiol Img 2012; 5:305-316.

Mangual J, Domenichini F, Pedrizzetti G. Describing the highly 3D flow in the right ventricle. ABME 2012; 40:1790-1801.

Cimino S, Pedrizzetti G, Tonti G, Canali E, Petronilli V, De Luca L, Iacoboni C, Agati L. In vivo Analysis of Intraventricular Fluid Dynamics in Healthy Hearts. Eur J Mech B/Fluids 2012; 35:40-46. (Special Issue: Cardiovascular Flows).

Vukicevic M, Fortini S, Querzoli G, Cenedese A, Pedrizzetti G. Experimental study of the asymmetric heart valve prototype. Eur J Mech B/Fluids 2012; 35:54-60. (Special Issue: Cardiovascular Flows).

Mangual J, Domenichini F, Pedrizzetti G. Three dimensional numerical assessment of the right ventricular flow using 4D echocardiography boundary data. Eur J Mech B/Fluids 2012; 35:25-30. (Special Issue: Cardiovascular Flows).

2011

De Luca A, Stefani L, Pedrizzetti G, Pedri S, Galanti G. The effect of exercise training on left ventricular function in young elite athletes. Cardiovascular Ultrasound 2011; 9:27.

Vukicevic M, Pedrizzetti G. On the opening of a wall-mounted leaflet by a single flow pulse. Phys Rev E 2011; 84:017301.

Hor KN, Baumann R, Pedrizzetti G, Tonti G, Gottliebson WM, Taylor M, Benson W, Mazur W. Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking. JoVE 2011; 48, doi: 10.3791/2356. (as a consultant)

Vukicevic M, Pedrizzetti G. Role of inertia in the interaction between oscillatory flow and a wall-mounted leaflet. Phys Rev E 2011; 83 (1):016310.

Domenichini F, Pedrizzetti G. Intraventricular vortex flow changes in the infarcted left ventricle. Computer Methods in Biomechanics and Biomedical Engineering 2011; 14(1):95-101

de Tullio MD, Pedrizzetti G, Verzicco R. On the influence of the aortic root geometry on blood flow after a bileaflet mechanical heart valve implant: a numerical study. Acta Mechanica 2011; 216:147-163.

2010

Pedrizzetti G. Vortex formation out of two-dimensional orifices. J Fluid Mech 2010; 655:198-216.

Faludi R, Szulik M, D hooge J, Herijgers P, Rademakers F, Pedrizzetti G, Voigt J-U. Left ventricular flow patterns in healthy subjects and patients with prosthetic mitral valves: An in vivo study using echocardiographic particle image velocimetry. J Thorac Cardiovasc Surg 2010; 139:1501-1510.

Pedrizzetti G, Domenichini F, Tonti G. On the left ventricular vortex reversal after mitral valve replacement. Ann Biomed Eng 2010; 38:769-773.

Kheradvar A, Houle H, Pedrizzetti G, Tonti G, Belcik T, Ashraf M, Lindner J, Gharib M, Sahn D. Echographic Particle Image Velocimetry: a novel technique for quantification of left ventricular blood vorticity pattern. J Am Soc Echocardiogr 2010; 23:86-94.

2009

Stefani L, Pedrizzetti G, De Luca A, Mercuri R, Innocenti G, Galanti G. Real-time Evaluation of Longitudinal Peak Systolic Strain (Speckle Tracking Measurement) in Left and Right Ventricles of Athletes. Cardiovascular Ultrasound 2009; 7:17.

Stefani L, De Luca A, Maffulli N, Mercuri R, Innocenti G, Suliman I, Toncelli L, Vono MC, Cappelli B, Pedri S, Pedrizzetti G, Galanti G. Speckle tracking for left ventricle performance in young athletes with bicuspid aortic valve and mild aortic regurgitation. Eur J Echocard 2009; 10:527-531.

2008

[Cover image]: J Am Coll Cardiol Img 2008; 1(6).

Hong GR, Pedrizzetti G, Tonti G, Li P, Wei Z, Kim JK, Bawela A, Liu S, Chung N, Houle H, Narula J, Vannan MA. Characterization and Quantification of Vortex Flow in the Human Left Ventricle by Contrast Echocardiography Using Vector Particle Image Velocimetry. JACC Cardiov Imaging 2008; 1:705-717.

Stefani L, Toncelli L, Di Tante V, Vono MCR, Moretti A, Cappelli B, Pedrizzetti G, Galanti G. Supernormal functional reserve of apical segments in elite soccer players : an ultrasound speckle tracking handgrip stress study. Cardiovascular Ultrasound 2008; 6:14.

2007

Pedrizzetti G, Domenichini F. Asymmetric opening of a simple bi-leaflet valve.Phys Rev Lett 2007; 98:214503.

Stefani L, Toncelli L, Gianassi M, Manetti P, Di Tante V, Vono MCR, Moretti A, Cappelli B, Pedrizzetti G, Galanti G. Two-dimensional tracking and TDI are consistent methods for evaluating myocardial longitudinal peak strain in left and right ventricle basal segments in athletes. Cardiovascular Ultrasound 2007; 5:7.

Domenichini F, Querzoli G, Cenedese A, Pedrizzetti G. Combined experimental and numerical analysis of the flow structure into the left ventricle. J Biomech 2007; 40:1988-1994.

2006

Pedrizzetti G, Domenichini F. Flow-driven opening of a valvular leaflet. J Fluid Mech 2006; 569:321-330.

Pedrizzetti G. Left Ventricular Fluid Dynamics. Ercoftac Bull 2006; 68:25-28.

Di Bello V, Santini F, Di Cori A, Pucci A, Palagi C, Delle Donne MG, Giannetti M, Talini E, Nardi C, Pedrizzetti G, Fierabracci P, Vitti P, Pinchera A, Balbarini A. Relationship between preclinical abnormalities of global and regional left ventricular function and insulin resistance in severe obesity: a Color Doppler Imaging Study. International Journal of Obesity 2006; 30:948-956.

2005

Vannan MA, Pedrizzetti G, Li P, Gurudevan S, Houle H, Main J, Jackson J, Nanda N. Effect of Cardiac Resynchronization Therapy on Longitudinal and Circumferential Left Ventricular Mechanics by Velocity Vector Imaging: Description and Initial Clinical Application of a Novel Method Using High-Frame Rate B-Mode Echocardiographic Images. Echocardiography 2005; 22:826-830.

Pedrizzetti G, Domenichini F. Nature optimizes the swirling flow in the human left ventricle. Phys Rev Lett 2005; 95:108101.

Domenichini F, Pedrizzetti G, Baccani B. Three-dimensional filling flow into a model left ventricle. J Fluid Mech 2005; 539:179-198.

Pedrizzetti G. Kinematic characterization of valvular opening. Phys Rev Lett 2005; 94:194502.

2004

Agati L, Tonti G, Pedrizzetti G, Magri F, Funaro S, Madonna M, Celani F, Messager T, Broillet A. Clinical application of quantitative analysis in real-time MCE. Eur J Echocardiography 2004; 45:S9-S15.

Agati L, Tonti G, Pedrizzetti G. Clinical Application of Quantitative Analysis in Myocardial Contrast Echocardiography. In: Contrast Echocardiography in Clinical Practice, JL Zamorano, MA Garcia-Fernandez eds. Springer 2004. ISBN 88-470-0237-0.

Tortoriello A, Pedrizzetti G. Flow-tissue interaction with compliance mismatch in a model stented artery. J Biomechanics 2004; 37:1-11.

2003

[Edited Book]: Pedrizzetti G, Perktold K (editors). CardioVascular Fluid Mechanics. Springer-Verlag, Wien New York 2003 (ISBN 3-211-00538-2).

Grigioni M, Tonti G, Pedrizzetti G, Daniele C, D'Avenio G. In vitro assessment of a new algorithm for quantitative echo measurement of heart valve regurgitant jet. Proc. SPIE Int. Soc. Opt. Eng. 2003; 5035:287-297.

Bolzon G, Zovatto L, Pedrizzetti G. Birth of three-dimensionality in a pulsed jet through a circular orifice. J Fluid Mech 2003; 493:209-218.

Baccani B, Domenichini F, Pedrizzetti G. Model and influence of mitral valve opening during the left ventricular filling. J Biomechanics 2003; 36:355-361.

2002

Baccani B, Domenichini F, Pedrizzetti G. Vortex dynamics in a model left ventricle during filling. Eur J Mech B/Fluids 2002; 21:527-543.

Amodeo A, Grigioni M, Oppido G, Daniele C, D'Avenio G, Pedrizzetti G, Giannico S, Filippelli S, Di Donato R. The beneficial vortex and best spatial arrangement in total extracardiac cavopulmonary connection. J Thorac Cardiovasc Surg 2002; 124:471-478.

Pedrizzetti G, Domenichini F, Tortoriello A, Zovatto L. Pulsatile flow inside moderately elastic arteries, its modelling and effects of elasticity. Computer Methods in Biomechanics and Biomedical Engineering 2002; 5:219-231.

Baccani B, Domenichini F, Pedrizzetti G, Tonti G. Fluid dynamics of the left ventricular filling in dilated cardiomiopathy. J Biomechanics 2002; 35:665-671.

Bolzon G, Pedrizzetti G, Grigioni M, Zovatto L, Daniele C, D'Avenio G. Flow on the symmetry plane of a total cavo-pulmonary connection. J Biomechanics 2002; 35:595-608.

2001

Tonti G, Pedrizzetti G, Trambaiolo P, Salustri A. Space and time dependency of inertial and convective contribution to the transmitral pressure drop during ventricular filling. J Am Coll Card 2001; 38:290-291.

Zovatto L, Pedrizzetti G. Flow about a circular cylinder between parallel walls. J Fluid Mech 2001; 440:1-25.

2000

Pedrizzetti G, Vassilicos JC. Interscale transfer in 2D compact vortices. J Fluid Mech 2000; 406:109-129.

1999

Pedrizzetti G. Quadratic Markov modeling for intermittent turbulence. Phys Fluids 1999; 11:1694-1696.

1998

Pedrizzetti G. Fluid flow in a tube with an elastic membrane insertion. J Fluid Mech 1998; 375:39-64.

Pentek A, Kadtke JB, Pedrizzetti G. Dynamical control for capturing vortices near bluff bodies. Phys Rev E 1998; 58:1883-1898.

Domenichini F, Pedrizzetti G. Impulsively started flow separation in wavy-walled tubes. J Fluid Mech 1998; 359:1-22.

1997

Pedrizzetti G, Domenichini F. Impulsive and pressure-driven transient flows in closed ducts. Phys Fluids 1997; 9:3575-3577.

Domenichini F, Pedrizzetti G, de Bernardinis B. A model for pressure distribution over obstacles due to separated flow. J Wind Eng Ind Aerod 1997; 66:51-67.

1996

Pedrizzetti G. Unsteady tube flow over an expansion. J Fluid Mech 1996; 310:89-111.

Pedrizzetti G, Novikov EA, Praskovsky AA. Self-similarity and probability distributions of turbulent intermittency. Phys Rev E 1996; 53:475-484.

1995

Kadtke J, Pentek A, Pedrizzetti G. Controlled capture of a continuous vorticity distribution. Phys Lett A 1995; 204:108-114.

1994

Luithardt HH, Kadtke JB, Pedrizzetti G. Capture of vortices by a moving body II: bound pair model. Chaos 1994; 4:681-691.

Pedrizzetti G, Novikov EA On Markov modeling of turbulence. J Fluid Mech 1994; 280:69-93.

1993

Pedrizzetti G, Kadtke JB, Luithardt HH. Chaotic trapping phenomena in extended systems. Phys Rev E 1993; 48:3299-3308.

Pedrizzetti G, Novikov EA. Instability and chaos in axisymmetric vortex-body interactions. Fluid Dynamics Research 1993; 12:129-151. (Part of PhD Thesis)

Sakay Y, Hunt JCR, Fung JCH, Pedrizzetti G, et al. Modelling of the diffusion of fluid particles in turbulent flows approaching a circular cylinder by random Fourier modes and random flight. Applied Scientific Research 1993; 51:547-553.

1992

Pedrizzetti G. Close interaction between a vortex filament and a rigid sphere. J Fluid Mech 1992; 245:701-722. (Part of PhD Thesis)

Pedrizzetti G. Insight into Singular Vortex Flows. Fluid Dynamics Research 1992; 10:101-116. (Part of PhD Thesis)

1991

Pedrizzetti G. Space Temporal Maps for Vortical Flow Field Construction. Meccanica 1991; 26:33-36.

1990

Hunt JCR, Kawai H, Ramsey SR, Pedrizzetti G, Perkins RJ. A Review of Velocity and Pressure Fluctuations in Turbulent Flows around Bluff Bodies. J Wind Eng Ind Aerod 1990; 35:49-85.